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Updated: Aug 16, 2026

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
Published on: May 1, 2015
[Portal cavernoma and intestinal lymphangiectasis]
Insights
A child with a rare vascular malformation, portal cavernoma, experienced growth issues and intestinal lymphangiectasia. Treatment via splenorenal shunt improved lymphopenia, suggesting a link between portal hypertension and lymphangiectasia.
Area of Science:
- Pediatric Gastroenterology
- Vascular Malformations
- Hepatology
Background:
- Portal cavernoma, a rare venous malformation, can lead to portal hypertension.
- Portal hypertension is associated with various gastrointestinal complications.
- Growth retardation is a significant concern in pediatric patients with chronic conditions.
Observation:
- A pediatric case presented with portal cavernoma and significant growth retardation.
- Intestinal lymphangiectasia was identified as a comorbidity in this patient.
- Lymphopenia was noted as a clinical finding.
Findings:
- The study proposes intestinal lymphangiectasia may be secondary to portal hypertension.
- A splenorenal shunt procedure was performed.
- Post-shunt, a notable improvement in lymphopenia was observed.
Implications:
- This case suggests a potential pathophysiological link between portal cavernoma, portal hypertension, and intestinal lymphangiectasia.
- Surgical intervention for portal hypertension may positively impact associated lymphatic abnormalities.
- Further research is warranted to elucidate the mechanisms connecting these conditions.
Abstract:
A child is described with a portal cavernoma and marked growth retardation who was found to have intestinal lymphangiectasia. It is proposed that the lymphangiectasia may be secondary to portal hypertension. This suggestion is supported by the improvement in lymphopenia after a splenorenal shunt cavernome.
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