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Updated: Oct 3, 2026

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Bacterial Artificial Chromosomes: A Functional Genomics Tool for the Study of Positive-strand RNA Viruses
Published on: December 29, 2015
Appearance of defective virions in clones of reovirus
Journal of Virology
|November 1, 1970
Abstract:
Virus obtained from five plaques of reovirus was serially passaged in L cells. Defective virions arose in each clone by the seventh passage. Such defective virions lacked the largest of the 10 segments of the double-stranded ribonucleic acid genome.

