Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Automated nerve fiber counting using an array processor in a multi-minicomputer system.

G K Frykman, H G Rutherford, I R Neilsen

    Journal of Medical Systems
    |January 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    External fixators for treatment of unstable wrist fractures. A biomechanical, design feature, and cost comparison.

    Hand clinics·1993
    Same author

    The quest for better recovery from peripheral nerve injury: current status of nerve regeneration research.

    Journal of hand therapy : official journal of the American Society of Hand Therapists·1993
    Same author

    Treatment of scaphoid nonunion with casting and pulsed electromagnetic fields: a study continuation.

    The Journal of hand surgery·1992
    Same author

    Irreducible epiphyseal plate fracture of the distal ulna due to interposition of the extensor carpi ulnaris tendon. A case report.

    Clinical orthopaedics and related research·1990
    Same author

    A new class of ring avulsion injuries.

    The Journal of hand surgery·1989
    Same author

    Comparison of eleven external fixators for treatment of unstable wrist fractures.

    The Journal of hand surgery·1989
    Same journal

    Security Analysis of a Federated Learning Framework for Medical Image-to-Image Translation.

    Journal of medical systems·2026
    Same journal

    Correction to: Designing Operating Rooms as an Integrated Socio-Technical Ecosystem: Practical Lessons from a High-Volume Tertiary Center.

    Journal of medical systems·2026
    Same journal

    AI-enabled clinical decision support in breast cancer care: a blinded multicenter benchmarking study comparing medically specialized with a general-purpose system.

    Journal of medical systems·2026
    Same journal

    Starmate: A Lightweight AI Assistant for Autism Caregivers Developed and Evaluated Through a User-Centered Mixed-Methods Framework.

    Journal of medical systems·2026
    Same journal

    Predicting the Predictor: Unresolved Validity Threats in LLM-Based ASA Classification.

    Journal of medical systems·2026
    Same journal

    Development and Internal Validation of a Vectorcardiography-Augmented Model for 12-Month Major Adverse Cardiovascular Events in Chronic Heart Failure.

    Journal of medical systems·2026
    See all related articles

    This study introduces an automated image-processing method for counting regenerated nerve fibers after peripheral nerve repair. This technique aids in quantifying nerve regeneration and assessing functional recovery in animal models.

    Area of Science:

    • Neuroscience
    • Biomedical Engineering
    • Medical Imaging

    Background:

    • Peripheral nerve injuries can impair motor and sensory functions.
    • Optimizing nerve repair, particularly fascicular matching, may improve functional recovery.
    • Quantitative assessment of nerve regeneration is crucial for evaluating repair efficacy.

    Purpose of the Study:

    • To develop and implement image-processing algorithms for automated nerve fiber counting.
    • To quantitatively assess nerve regeneration following peripheral nerve repair in a feline model.
    • To establish parameters for evaluating functional recovery, including nerve fiber count and end-organ reinnervation.

    Main Methods:

    • Processing digitized micrographs of transected and repaired feline sciatic nerves using edge enhancement, thresholding, template matching, and peak detection.

    Related Experiment Videos

  • Automated counting of nerve fibers proximal and distal to the repair site.
  • Utilizing the Multi-MiniComputer System (MMCS) with an AP-120B array processor and pipeline processing for high throughput.

    • Main Results:

    • Successful implementation of image-processing algorithms for automated nerve fiber quantification.
    • Generation of data arrays for estimating nerve fiber counts and assessing regeneration proportions.
    • Demonstration of improved throughput using advanced computing systems for nerve analysis.

    Conclusions:

    • The developed image-processing techniques provide a quantitative method for assessing nerve regeneration.
    • Automated nerve fiber counting can aid in evaluating the success of peripheral nerve repair strategies.
    • Efficient computational methods are essential for analyzing complex biological data in nerve regeneration studies.