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[Principles of therapeutic trials (author's transl)]
Revue Francaise Des Maladies Respiratoires
|July 1, 1979
Abstract:
Therapeutic trials aim at comparing the effectiveness of two therapeutic attitudes. The problems involved are considered: comparability requirements of the groups, assured by randomization, which raises ethical questions. The need of a "sufficient" number of subjects, often imposing cooperative trials, is then discussed. Finally, it is necessary to define the disease and patients, the therapeutic possibilities, and judgement criteria.