[Histopathological diagnosis and clinical significance of endometrial hyperplasia]

Histological analysis of 266 hyperplastic endometria obtained by curettage revealed the following forms of hyperplasia: simplex 29.3%, cystic 50%, adenomatous 18.4, and atypical 2.2% (according to the classification accepted by the authors). Mild forms of endometrial hyperplasia (simple and cystic) recede in most cases spontaneously or after therapy and rarely turn into endometrial adenocarcinoma, whereas severe forms of hyperplasia (adenomatous and atypical), unless treated, often turn into endometrial carcinoma. The etiology, some clinical manifestations, and therapy of this condition of the endometrium are reviewed.