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[Successful nifedipine therapy in coronary spasm]

Acta Medica Austriaca
|January 1, 1979
PubMed

Insights

Prinzmetal

Area of Science:

  • Cardiology
  • Clinical Medicine

Background:

  • Prinzmetal's angina is a condition characterized by chest pain due to transient coronary artery spasm.
  • Typical presentation involves ST-segment elevation on electrocardiogram (ECG) during episodes.

Observation:

  • A 51-year-old male presented with symptoms consistent with Prinzmetal's angina.
  • Electrocardiogram (ECG) showed ST-elevation and ventricular ectopies during chest pain episodes.
  • Coronary arteriography identified spasm in a normal left anterior descending artery.

Findings:

  • The patient experienced recurrent chest pain attributed to coronary artery spasm.
  • A combination therapy of Nifedipine and Isosorbide dinitrate was initiated.

Implications:

  • This case highlights the effectiveness of combined Nifedipine and Isosorbide dinitrate in managing Prinzmetal's angina.
  • Successful treatment resulted in a 9-month pain-free period for the patient.
  • Coronary artery spasm can occur in apparently normal arteries and is treatable.

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