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Updated: Jan 27, 2026

11:03
Measurement of Fatty Acid β-Oxidation in a Suspension of Freshly Isolated Mouse Hepatocytes
Published on: September 9, 2021
4.4K
[Oxidative deamination of beta-methylaspartic acid]
Summary
Beta-methyl-aspartic acid is processed by beef kidney D-aspartate oxidase. This enzyme
Area of Science:
- Biochemistry
- Enzymology
Context:
- Beef kidney D-aspartate oxidase is an enzyme with known substrate specificities.
- Oxidative deamination is a key metabolic pathway.
Purpose:
- To investigate the enzymatic activity of beef kidney D-aspartate oxidase on beta-methyl-aspartic acid.
- To elucidate the reaction products of this enzymatic process.
Summary:
- Beta-methyl-aspartic acid serves as a substrate for beef kidney D-aspartate oxidase.
- The enzyme catalyzes oxidative deamination, yielding an intermediate product.
- This intermediate product spontaneously decarboxylates to form alpha-keto-butyric acid.
Impact:
- Provides insight into the substrate range of D-aspartate oxidase.
- Clarifies the metabolic fate of beta-methyl-aspartic acid.
- Contributes to understanding amino acid metabolism and enzymatic reactions.
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