Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Dedifferentiated chondrosarcomas.

M Campanacci, F Bertoni, R Capanna

    Italian Journal of Orthopaedics and Traumatology
    |December 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    Dedifferentiated chondrosarcoma is a rare and aggressive bone cancer. Radical surgical removal, such as amputation, offers the only effective treatment for this challenging neoplasm.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    A retrospective analysis of phase I and phase I/II investigator-initiated clinical trials conducted by the Swiss Group for Clinical Cancer Research (SAKK).

    ESMO open·2025
    Same author

    A systematic review of contemporary phase I trials in patients with lymphoma.

    Critical reviews in oncology/hematology·2022
    Same author

    Overcoming PARPi resistance: Preclinical and clinical evidence in ovarian cancer.

    Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy·2021
    Same author

    Induction TPF followed by concomitant treatment versus concomitant treatment alone in locally advanced head and neck cancer. A phase II-III trial.

    Annals of oncology : official journal of the European Society for Medical Oncology·2017
    Same author

    Emerging therapies provide new opportunities to reshape the multifaceted interactions between the immune system and lymphoma cells.

    Leukemia·2016
    Same author

    Combination of the MEK inhibitor pimasertib with BTK or PI3K-delta inhibitors is active in preclinical models of aggressive lymphomas.

    Annals of oncology : official journal of the European Society for Medical Oncology·2016
    Same journal

    Early diagnosis of congenital dysplasia of the infant hip by means of ultrasound screening.

    Italian journal of orthopaedics and traumatology·1993
    Same journal

    Ulna non-union leading to Monteggia fracture deformity. Two cases of slowly developing radial head luxation.

    Italian journal of orthopaedics and traumatology·1993
    Same journal

    Scanning electron microscopy study of articular cartilage in the evolution of hip arthritis.

    Italian journal of orthopaedics and traumatology·1993
    Same journal

    Remarks on the complications following ACL reconstruction using synthetic ligaments.

    Italian journal of orthopaedics and traumatology·1993
    Same journal

    Long-term results of cemented and screwed acetabular components.

    Italian journal of orthopaedics and traumatology·1993
    Same journal

    Post-operative intervertebral discitis. Evaluation of 12 cases and study of ESR in the normal postoperative period.

    Italian journal of orthopaedics and traumatology·1993
    See all related articles

    Area of Science:

    • Orthopedic Oncology
    • Skeletal Pathology
    • Cancer Research

    Background:

    • Dedifferentiated chondrosarcoma is a rare malignant bone tumor.
    • It presents with aggressive clinical behavior and poor prognosis.
    • Understanding its features is crucial for effective management.

    Purpose of the Study:

    • To describe the key clinical, radiographic, and histological characteristics of dedifferentiated chondrosarcoma.
    • To highlight the prognostic implications of this rare sarcoma.
    • To emphasize the critical role of radical surgical intervention.

    Main Methods:

    • Retrospective case series analysis.
    • Review of twenty-five cases of dedifferentiated chondrosarcoma.
    • Correlation of clinical, imaging, and pathological findings.

    Related Experiment Videos

    Main Results:

    • The study details the principal clinical presentations.
    • Radiographic and histological features of dedifferentiated chondrosarcoma are illustrated.
    • Prognosis is noted to be particularly grave.

    Conclusions:

    • Dedifferentiated chondrosarcoma requires prompt and aggressive management.
    • Radical tumor removal via amputation or disarticulation is the primary therapeutic approach.
    • Early diagnosis and surgical intervention are vital for patient outcomes.