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Anthelmintic efficiency of fenbendazole in equines
Journal of the South African Veterinary Association
|December 1, 1979
Summary
Fenbendazole (FBZ) effectively treated various gastrointestinal parasites in donkeys and horses at a 10 mg/kg dose. This broad-spectrum anthelmintic demonstrated high efficacy against numerous genera and species, including Cyathostominae subfamily members.
Area of Science:
- Veterinary Parasitology
- Pharmacology
Background:
- Gastrointestinal nematodes pose significant health risks to equids.
- Effective and safe anthelmintics are crucial for equine welfare and performance.
Purpose of the Study:
- To evaluate the efficacy of fenbendazole (FBZ) against specific equine parasites.
- To assess the effectiveness of FBZ administered orally and via a medicated lick.
Main Methods:
- Donkeys were administered a single oral dose of FBZ (10 mg/kg).
- Another group of donkeys consumed FBZ via a medicated lick to achieve 10 mg/kg body mass.
- Parasite efficacy was assessed against various genera and species of nematodes and Oxyuris equi.
Main Results:
- Fenbendazole (FBZ) demonstrated high efficacy against adult Cyathostomum, Cylicocyclus, Cylicostephanus, Cylicodontophorus, Poteriostomum, Cabellonema, Craterostomum, and Triodontophorus.
- FBZ was also highly effective against Habronema majus, Habronema musca, Strongylus vulgaris, Oxyuris equi, and the subfamily Cyathostominae.
- In horses, FBZ at 10 mg/kg was highly effective against Gyalocephalus capitatus, Oesophagodontos robustus, and Parascaris equorum.
Conclusions:
- Fenbendazole is a highly effective broad-spectrum anthelmintic for treating common equine parasites.
- Both single oral dosing and medicated lick administration of FBZ achieved high efficacy.