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Updated: Jun 27, 2026
Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer
Published on: July 29, 2010
Abstract:
Extracts of human colonic adenocarcinomata were made with perchloric acid and shown to contain antigens which were not present in pooled samples of normal colonic mucosa or in healthy colonic mucosa from patients providing the tumours. Antisera prepared against the tumour extracts gave two precipitin lines on immunodiffusion, and antiserum prepared in Montreal according to the methods devised by Gold and Freedman (1965a and b) also gave two lines of precipitation when tested against some of these extracts; one of these precipitin lines gave a reaction of identity with that given by the antiserum produced here. The results suggest that perchloric acid may extract two antigens from colonic carcinomata.
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Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and solid...