Folic acid analogs. Modifications in the benzene-ring region. 1. 2'- and 3'-azafolic acids

Id helix-loop-helix proteins antagonize pax transcription factor activity by inhibiting DNA binding.

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Inhibition of hepatitis C virus (HCV)-RNA-dependent translation and replication of a chimeric HCV poliovirus using synthetic stabilized ribozymes.

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Anhydroretinol, a retinoid active in preventing mammary cancer induced in rats by N-methyl-N-nitrosourea.

Oncology reports·1998

Interaction of transcription factors with serum response factor. Identification of the Elk-1 binding surface.

The Journal of biological chemistry·1998

Retinyl substituted-benzyl ethers. Inhibition of mammary carcinogenesis by retinyl 3,4,5-trimethoxybenzyl ether (RTMBE).

Anti-cancer drug design·1998

Metabolism in human cells of the D and L enantiomers of the carbocyclic analog of 2'-deoxyguanosine: substrate activity with deoxycytidine kinase, mitochondrial deoxyguanosine kinase, and 5'-nucleotidase.

Antimicrobial agents and chemotherapy·1998

Structural and Mechanistic Studies of ADEPs Yield Potent Antibacterials and a Drug Formulation Strategy for Tuberculosis.

Journal of medicinal chemistry·2026

A 177Lu-Labeled Circular Bivalent Aptamer for PTK7-Targeting Radionuclide Therapy in Ovarian Cancer and Orthotopic Hepatoblastoma.

Journal of medicinal chemistry·2026

From Fragment Hit to Clinical Candidate: Discovery of Dual H1R/H4R Ligands with Superior Efficacy in Allergic Conjunctivitis.

Journal of medicinal chemistry·2026

Potent Anticancer Tethered Organorhodium(III) Complexes Target the Mitochondria.

Journal of medicinal chemistry·2026

Discovery of a Covalent NLRP3 LRR-Domain Probe: Reversing Renal Fibrosis via Immunometabolic Reprogramming in Organoid and Murine Models.

Journal of medicinal chemistry·2026

Lead Optimization of Multimutant KRAS Switch-II Pocket Macrocyclic Inhibitors via Isosteric Replacement to Improve ADME and Oral Exposure.

Journal of medicinal chemistry·2026

Visible Light-Mediated Sulfonylation of Enamides: Synthesis of (E)-β-Amidovinyl Sulfones.

Chemistry, an Asian journal·2026

A blood-brain barrier-penetrating NIR fluorescent probe enables cross-model optical imaging of H2O2 in three neuroinflammation-related experimental mice models of brain injury.

Analytica chimica acta·2026

Microbubble-enhanced ozone/peroxymonosulfate oxidation for DEET degradation: Mass transfer-reaction coupled radical generation, oxidant contributions and energy efficiency.

Water research·2026

Resveratrol alleviates osteoarthritis progression by inhibiting NLRP3 inflammasome response via the AMPK/PPARγ signaling pathway.

International journal of molecular medicine·2026

Anti-Markovnikov Hydroamination of Vinylpyridines via a Novel Photocatalytic Strategy.

Molecules (Basel, Switzerland)·2026

Visible light-induced oxygen atom transfer into C-CL bond of acyl chlorides for homolytic cleavage.

Nature communications·2026

Related Experiment Videos

Folic acid analogs. Modifications in the benzene-ring region. 1. 2'- and 3'-azafolic acids

Related Concept Videos

Id helix-loop-helix proteins antagonize pax transcription factor activity by inhibiting DNA binding.

Inhibition of hepatitis C virus (HCV)-RNA-dependent translation and replication of a chimeric HCV poliovirus using synthetic stabilized ribozymes.

Anhydroretinol, a retinoid active in preventing mammary cancer induced in rats by N-methyl-N-nitrosourea.

Interaction of transcription factors with serum response factor. Identification of the Elk-1 binding surface.

Retinyl substituted-benzyl ethers. Inhibition of mammary carcinogenesis by retinyl 3,4,5-trimethoxybenzyl ether (RTMBE).

Metabolism in human cells of the D and L enantiomers of the carbocyclic analog of 2'-deoxyguanosine: substrate activity with deoxycytidine kinase, mitochondrial deoxyguanosine kinase, and 5'-nucleotidase.

Structural and Mechanistic Studies of ADEPs Yield Potent Antibacterials and a Drug Formulation Strategy for Tuberculosis.

A 177Lu-Labeled Circular Bivalent Aptamer for PTK7-Targeting Radionuclide Therapy in Ovarian Cancer and Orthotopic Hepatoblastoma.

From Fragment Hit to Clinical Candidate: Discovery of Dual H1R/H4R Ligands with Superior Efficacy in Allergic Conjunctivitis.

Potent Anticancer Tethered Organorhodium(III) Complexes Target the Mitochondria.

Discovery of a Covalent NLRP3 LRR-Domain Probe: Reversing Renal Fibrosis via Immunometabolic Reprogramming in Organoid and Murine Models.

Lead Optimization of Multimutant KRAS Switch-II Pocket Macrocyclic Inhibitors via Isosteric Replacement to Improve ADME and Oral Exposure.

Visible Light-Mediated Sulfonylation of Enamides: Synthesis of (E)-β-Amidovinyl Sulfones.

A blood-brain barrier-penetrating NIR fluorescent probe enables cross-model optical imaging of H2O2 in three neuroinflammation-related experimental mice models of brain injury.

Microbubble-enhanced ozone/peroxymonosulfate oxidation for DEET degradation: Mass transfer-reaction coupled radical generation, oxidant contributions and energy efficiency.

Resveratrol alleviates osteoarthritis progression by inhibiting NLRP3 inflammasome response via the AMPK/PPARγ signaling pathway.

Anti-Markovnikov Hydroamination of Vinylpyridines via a Novel Photocatalytic Strategy.

Visible light-induced oxygen atom transfer into C-CL bond of acyl chlorides for homolytic cleavage.

Related Experiment Videos

Folic acid analogs. Modifications in the benzene-ring region. 1. 2'- and 3'-azafolic acids

Related Concept Videos

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