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Related Experiment Videos

Pyrexial reactions during haemodialysis.

P J Robinson, S M Rosen

    British Medical Journal
    |March 6, 1971
    PubMed
    Summary

    Pyrexial reactions during hemodialysis occurred epidemically in hospitals, unlike home dialysis. Bacterial growth or water quality did not correlate with these reactions, suggesting other causes.

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    Area of Science:

    • Nephrology
    • Infectious Disease Epidemiology

    Background:

    • Pyrexial reactions are a concern during hemodialysis.
    • Understanding the incidence and causes of these reactions is crucial for patient safety.

    Purpose of the Study:

    • To investigate the characteristics, circumstances, and treatment of pyrexial reactions in hemodialysis patients.
    • To identify potential correlations between pyrexial reactions and various factors including dialysis equipment, water quality, and bacterial contamination.

    Main Methods:

    • A retrospective study of 450 pyrexial reactions over two and a half years in 468 patient-months.
    • Analysis of blood cultures, dialysis equipment types, and water quality parameters.
    • Comparison between in-hospital and home dialysis patients.

    Main Results:

    • Pyrexial reactions exhibited an epidemic pattern within the hospital unit.
    • Home dialysis patients experienced significantly fewer reactions than in-hospital patients.
    • No significant correlation was found between reactions and bacterial growth in blood cultures or dialysis equipment type.
    • Reactions with disposable coil and recirculating single-pass (R.S.P.) systems differed from the Kiil kidney system.
    • Water quality, including albuminoid nitrogen content and deionization, did not affect reaction incidence.

    Conclusions:

    • Pyrexial reactions in hemodialysis are complex and appear to have an epidemic pattern in hospital settings.
    • Factors beyond bacterial contamination and water quality, such as dialysis delivery systems, may influence reaction occurrence.
    • Further research is needed to elucidate the specific causes and develop preventative strategies for pyrexial reactions in hemodialysis.

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