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[Changes in CSF dynamics and performance tests after head injuries (author's transl)].

G Brambilla, G Sangiovanni, S Vender

    Rivista Di Patologia Nervosa E Mentale
    |July 1, 1979
    PubMed
    Summary

    Isotope cisternography revealed abnormal cerebrospinal fluid flow in head-injured patients, correlating with cognitive decline. Ventricular reflux and asymmetrical diffusion were common findings in patients with head trauma and subsequent neurological deficits.

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    Area of Science:

    • Neurology
    • Neurosurgery
    • Nuclear Medicine

    Background:

    • Head injuries can lead to long-term neurological deficits.
    • Assessing cerebrospinal fluid (CSF) dynamics is crucial for understanding post-traumatic brain changes.
    • Cognitive impairment following head trauma requires objective diagnostic tools.

    Purpose of the Study:

    • To investigate the correlation between cerebrospinal fluid (CSF) flow patterns and neuropsychological deficits in head-injured patients.
    • To evaluate the utility of isotope cisternography in identifying abnormalities after traumatic brain injury.
    • To correlate cisternographic findings with the need for and outcome of neurosurgical intervention.

    Main Methods:

    • Isotope cisternography using RISA and In111-DTPA was performed on 30 head-injured patients at least six months post-injury.

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  • Patients underwent psychodiagnostic testing, including Raven's Progressive Coloured Matrices and Immediate Memory Tests.
  • Cisternographic images were classified as normal, asymmetrical diffusion, or ventricular reflux and correlated with neuropsychological data.

    • Main Results:

    • Abnormal CSF flow patterns were observed in 25 out of 30 patients.
    • Ventricular reflux was present in 10 patients (5 surgically treated), and asymmetrical diffusion in 15 patients (11 surgically treated).
    • Neuropsychological test results showed progressive mental deterioration that strongly correlated with the cisternographic findings.

    Conclusions:

    • Isotope cisternography is a valuable tool for detecting cerebrospinal fluid (CSF) circulation abnormalities after head injury.
    • Abnormal CSF dynamics, particularly ventricular reflux and asymmetrical diffusion, are associated with significant cognitive impairment in head-injured individuals.
    • The study highlights the link between impaired CSF flow and neurological deficits, supporting the use of cisternography in the management of head trauma sequelae.