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Updated: Aug 18, 2026

Electrolytic Inferior Vena Cava Model (EIM) of Venous Thrombosis
Published on: July 12, 2011
Circannual rhythm of arterial and venous thromboembolic disease
Insights
Seasonal patterns significantly impact cardiovascular health, with higher rates of coronary and cerebral arterial diseases in winter compared to summer. This seasonal variation also affects venous thrombo-embolic disease.
Area of Science:
- Cardiovascular epidemiology
- Seasonal health variations
Background:
- Previous reports suggest seasonal variations in cardiovascular diseases.
- Coronary and cerebral arterial diseases exhibit differing annual morbidity and mortality patterns.
Purpose of the Study:
- To confirm seasonal variations in morbidity and mortality for coronary and cerebral arterial diseases.
- To investigate the circannual rhythm in venous thrombo-embolic disease.
Main Methods:
- Analysis of seasonal disease incidence and mortality data.
- Comparison of morbidity and mortality curves for coronary artery disease.
Main Results:
- Coronary and cerebral arterial diseases are significantly less common in summer than in winter.
- Morbidity and mortality curves for coronary artery disease show distinct seasonal shapes.
- A similar seasonal pattern was observed for venous thrombo-embolic disease.
Conclusions:
- Seasonal variations demonstrably affect the incidence and mortality of major arterial and venous diseases.
- Understanding these circannual rhythms is crucial for public health strategies and preventative care.
Abstract:
This study confirms previous reports of a seasonal variation in morbidity and mortality from coronary and cerebral arterial disease; these disorders are much less common in summer (e.g. July and August) than in winter (e.g. December and January). In coronary disease the shape of the curve for the annual morbidity is different from that for annual mortality and possible reasons for this are discussed. A similar circannual rhythm has been shown for venous thrombo-embolic disease.
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