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Updated: Aug 11, 2026
05:51
Measuring the Carotid to Femoral Pulse Wave Velocity (Cf-PWV) to Evaluate Arterial Stiffness
Published on: May 3, 2018
Summary
Elevated diastolic blood pressure (hypertension) increases risks for cardiovascular disease and all-cause mortality in men aged 30-59. These risks are evident even with moderate elevations and persist across different age groups within the study cohort.
Area of Science:
- Cardiovascular epidemiology
- Public health
Background:
- Hypertension is a major risk factor for cardiovascular disease (CVD).
- Long-term prospective studies are crucial for understanding CVD risk factors.
Purpose of the Study:
- To assess the long-term risks associated with hypertension.
- To evaluate the impact of diastolic blood pressure on cardiovascular morbidity and mortality.
Main Methods:
- Analysis of data from six prospective US cardiovascular disease studies (1948-1958).
- Follow-up of 6,640 men (aged 30-59) for 10 years.
- Recording of cardiovascular morbidity and all-cause/cardiovascular mortality.
Main Results:
- Diastolic blood pressure levels of 85-104 mm Hg were linked to increased total mortality.
- Elevated diastolic blood pressure correlated with higher rates of coronary heart disease deaths and major coronary events.
- Increased risk of cerebrovascular episodes was observed with higher diastolic blood pressure.
- The adverse effects were most pronounced in men in their fifties but also present in younger men.
Conclusions:
- Moderate elevations in diastolic blood pressure pose significant long-term health risks.
- Hypertension is a critical factor influencing cardiovascular outcomes across middle-aged men.
- Early identification and management of hypertension are vital for reducing CVD burden.
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