Jove
Visualize
Contact Us

Related Experiment Videos

Intelligence and blood pressure in the aged.

F Wilkie, C Eisdorfer

    Science (New York, N.Y.)
    |May 28, 1971
    PubMed
    Summary

    Diastolic hypertension is linked to significant intellectual decline in individuals in their 60s over a decade. This cognitive loss was not observed in peers with normal blood pressure, suggesting hypertension impacts aging cognition.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Immunoglobulins, cognitive status and duration of illness in alzheimer's disease.

    Neurobiology of aging·2013
    Same author

    Principles of community mental health in a rural setting: The Halifax County program.

    Community mental health journal·2013
    Same author

    Principles for the training of "new professionals" in mental health.

    Community mental health journal·2013
    Same author

    HIV-1 Infection, Neuroendocrine Abnormalities, and Clinical Outcomes.

    CNS spectrums·2008
    Same author

    Uncomplicated general anesthesia in the elderly results in cognitive decline: does cognitive decline predict morbidity and mortality?

    Medical hypotheses·2006
    Same author

    Aging and neuro-AIDS conditions and the changing spectrum of HIV-1-associated morbidity and mortality.

    Journal of clinical epidemiology·2001
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies

    Area of Science:

    • Gerontology
    • Neurology
    • Cardiovascular Medicine

    Background:

    • Hypertension is a prevalent condition in aging populations.
    • Cognitive function is a critical aspect of healthy aging.
    • The relationship between hypertension and cognitive decline requires further investigation.

    Purpose of the Study:

    • To investigate the association between diastolic hypertension and intellectual changes over a 10-year period.
    • To compare cognitive trajectories in hypertensive versus normotensive individuals.

    Main Methods:

    • Longitudinal study design.
    • Assessment of diastolic blood pressure and cognitive function (intelligence tests).
    • Follow-up over a 10-year period in individuals initially in their 60s and 70s.

    Main Results:

    • Diastolic hypertension correlated with significant intellectual loss in individuals in their 60s.
    • No such intellectual loss was found in normotensive peers.
    • Among those 70-79 years old, hypertensive individuals did not complete follow-up; normotensive individuals showed some decline.
    • Lower initial intelligence scores in hypertensive individuals predicted non-completion of follow-up.

    Conclusions:

    • Diastolic hypertension is associated with intellectual decline in older adults.
    • Hypertension may negatively impact cognitive aging.
    • Further research is needed to understand the mechanisms linking hypertension and cognitive changes.

    Related Experiment Videos