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Adequacy of expressed breast milk for early growth of preterm infants
Insights
Expressed breast milk showed slower growth in very premature infants during the first month compared to cow's milk formula. This suggests breast milk alone may be insufficient for optimal early growth in these vulnerable infants.
Area of Science:
- Neonatal nutrition
- Pediatric growth studies
- Infant feeding practices
Background:
- Preterm infants often experience suboptimal growth.
- Cow's milk formula is a common nutritional source for preterm infants.
- Expressed breast milk is also utilized but its efficacy for growth requires evaluation.
Purpose of the Study:
- To compare the early postnatal growth of preterm infants fed expressed breast milk versus cow's milk formula.
- To assess the impact of feeding regimen on weight, linear, and head circumference growth.
- To determine the adequacy of expressed breast milk for very immature preterm infants.
Main Methods:
- A randomized study involving 68 preterm infants (28-32 weeks and 33-36 weeks gestational age).
- Infants were assigned to receive either expressed breast milk or a standard cow's milk formula (Ostermilk 1).
- Growth parameters (weight, length, head circumference) were measured over two 1-month periods (birth-1 month, 1-2 months).
Main Results:
- Infants in the younger gestational age group (28-32 weeks) fed expressed breast milk exhibited slower growth rates in the first month compared to formula-fed infants.
- Growth rates became comparable between the two feeding groups in the second month for all infants.
- Older preterm infants (33-36 weeks) showed similar growth rates regardless of feeding type across both periods.
Conclusions:
- Expressed breast milk alone appears inadequate to support optimal growth in very immature preterm infants during the early postnatal period.
- Nutritional strategies may need to be adjusted for preterm infants based on gestational age and feeding type.
- Further research into optimizing nutrition for preterm infant growth is warranted.
Abstract:
Poor weight gain observed in preterm infants who were fed expressed breast milk compared with those fed a cows' milk formular prompted a detailed study of early postnatal growth in preterm infants fed these two milks. 68 infants were divided into two categories by gestational age at birth (i) 28-32 weeks (n=28), (ii) 33-36 weeks (n=40). They were randomly allocated to a feed of expressed breast milk or a milk formula (Ostermilk 1). Rates of weight gain, linear growth, and head circumference growth were evaluated over two periods: birth-1 month, 1-2 months. The younger group who were fed breast milk showed slower overall growth rates over the first month than those fed formula. In the second month, and for the older infants over both of the 2-monthly periods, growth rates were similar in the two feeding regimens. It is concluded that expressed breast milk is inadequate for the growth of very immature preterm infants during early postnatal life.
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