Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Temporal lobe aggression in rats.

J P Pinel, D Treit, L I Rovner

    Science (New York, N.Y.)
    |September 9, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Aggressive behavior can be linked to temporal lobe epilepsy. This study found increased aggression in rats with induced temporal lobe epileptic foci, suggesting a connection.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    No evidence for a protein-synthesis-dependent form of long-term fear memory: Translational inhibition and neural inactivation disrupt short- and long-term memory measures to the same degree.

    Neurobiology of learning and memory·2026
    Same author

    Extinction of conditioned defensive burying.

    Behavioural processes·2014
    Same author

    Α2 GABAA receptor sub-units in the ventral hippocampus and α5 GABAA receptor sub-units in the dorsal hippocampus mediate anxiety and fear memory.

    Neuroscience·2013
    Same author

    Anxiolytic- and antidepressant-like properties of ketamine in behavioral and neurophysiological animal models.

    Neuroscience·2009
    Same author

    Anxiolytic and antidepressant effects of intracerebroventricularly administered somatostatin: behavioral and neurophysiological evidence.

    Neuroscience·2008
    Same author

    Septal GABAergic and hippocampal cholinergic systems interact in the modulation of anxiety.

    Neuroscience·2003
    Same journal

    A native sulfur deposit in Gale crater, Mars.

    Science (New York, N.Y.)·2026
    Same journal

    Coordinated demise of harmful algal blooms.

    Science (New York, N.Y.)·2026
    Same journal

    Genetic effects put into context.

    Science (New York, N.Y.)·2026
    Same journal

    Bacteria share proteins to survive antibiotics.

    Science (New York, N.Y.)·2026
    Same journal

    Impacts shaped Earth's first continents.

    Science (New York, N.Y.)·2026
    Same journal

    Erratum for the Report "Covalently bonded single-molecule junctions with stable and reversible photoswitched conductivity" by C. Jia <i>et al</i>.

    Science (New York, N.Y.)·2026
    See all related articles

    Area of Science:

    • Neuroscience
    • Epilepsy Research
    • Behavioral Science

    Background:

    • Clinical observations suggest a link between temporal lobe epilepsy and aggression.
    • Experimental investigation of this link is challenging due to difficulties in achieving adequate control.

    Purpose of the Study:

    • To investigate the causal relationship between temporal lobe epilepsy and aggressive behavior.
    • To provide experimental evidence for the existence of temporal lobe aggression.

    Main Methods:

    • Epileptic foci were experimentally induced in the temporal lobe structures of rats.
    • Aggressive behavior was observed and compared between rats with temporal lobe foci, control rats, and rats with caudate foci.

    Main Results:

    Related Experiment Videos

  • Rats with experimentally induced temporal lobe epileptic foci exhibited increased aggressive behavior.
  • No significant increase in aggression was observed in control rats or those with caudate foci.

    • Conclusions:

    • Experimental induction of temporal lobe epileptic foci in rats leads to heightened aggression.
    • Findings support a potential neurobiological basis for aggression in temporal lobe epilepsy.