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Construction of Vapor Chambers Used to Expose Mice to Alcohol During the Equivalent of all Three Trimesters of Human Development
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Construction of Vapor Chambers Used to Expose Mice to Alcohol During the Equivalent of all Three Trimesters of Human Development

Published on: July 13, 2014

Maternal alcohol and neonatal health

W A Himwich, J S Hall, W F MacArthur

    Biological Psychiatry
    |August 1, 1977
    PubMed

    The disappearance of alcohol from blood following a single dose is a function of age, but by the time the animals are 90 days old the results are consistent from animal to animal. A single dose given to a pregnant female is distributed between fetus and maternal tissues and fluids, with a portion of the alcohol trapped in the amniotic fluid. Kittens born to mothers receiving alcohol during the last 2 weeks of pregnancy demonstrate hyperactivity, small size with unimpaired growth rate, and slow maturation of the righting reflex. It would require more experimentation to decide whether these changes are due to alcohol withdrawal or to toxic effects of the alcohol per se.

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