[Comparative study of 2 transplantable lines of murine L cells]

A continuous line of mouse L cells chronically infected with SV5 paramyxovirus differs from mouse L0 cells free from this virus in the mitotic activity and karyologic features. The LSV5 line is characterized by inhibition of the mitotic activity, a decrease in the number of chromosomes and the presence of the marker chromosome. LSV5 and L0 cell cultures do not differ in the number of pathological mitoses, structural aberrations of chromosomes and the cytomorphological picture. The persisting SV5 virus can be detected in LSV5 line cultures by a number of methods (immunofluorescence, virological methods, etc.).