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Related Concept Videos

Long-term Depression01:05

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Depression: Overview01:18

Depression: Overview

Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
Depressive Disorders: MDD and Dysthymia01:27

Depressive Disorders: MDD and Dysthymia

Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
Bipolar Disorder01:30

Bipolar Disorder

Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
Depressive Disorders: Etiology01:27

Depressive Disorders: Etiology

Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
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Relationship Growth01:27

Relationship Growth

Interpersonal relationships progress through stages, beginning with awareness and moving toward mutuality, where emotional connections deepen. While many relationships remain at moderate levels of mutuality, deeper connections form through self-disclosure, trust, and interdependence.Self-DisclosureSelf-disclosure involves revealing personal information, starting with surface-level details and gradually progressing to more intimate content. As trust grows, individuals feel more comfortable...

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Related Experiment Video

Updated: Jul 20, 2026

The Forced Swim Test as a Model of Depressive-like Behavior
05:42

The Forced Swim Test as a Model of Depressive-like Behavior

Published on: March 2, 2015

Twin relationships and depression.

M Paluszny, M L Selzer, A Vinokur

    The American Journal of Psychiatry
    |September 1, 1977
    PubMed
    Summary

    Twin studies reveal that greater closeness between twins is linked to lower depression levels. This research highlights the importance of relationships in understanding depressive symptoms.

    Area of Science:

    • Psychology
    • Behavioral Genetics

    Background:

    • Depression is a prevalent mental health concern.
    • Twin studies are valuable for exploring genetic and environmental influences on traits like depression.

    Purpose of the Study:

    • To investigate the relationship between interpersonal closeness and depressive symptoms in twins.
    • To assess depression levels in identical and fraternal twin pairs.

    Main Methods:

    • A questionnaire assessed demographic characteristics and twin relationship quality.
    • The Zung Self-Rating Depression Scale measured depressive symptoms.
    • Data were collected from 22 identical and 13 fraternal twin pairs.

    Main Results:

    • High agreement was observed across all measured variables within the twin pairs.

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    Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators

    Published on: March 21, 2018

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    A New Method for Inducing a Depression-Like Behavior in Rats
    07:57

    A New Method for Inducing a Depression-Like Behavior in Rats

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    Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators
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  • Depression levels in the sample were comparable to general population estimates.
  • A significant inverse correlation was found between closeness and depression.
  • Conclusions:

    • Interpersonal closeness may play a protective role against depression.
    • Future research should explore these relationships in diverse groups and longitudinal studies.