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Related Experiment Videos

Caudal anesthesia in infants.

S Z Hassan

    Anesthesia and Analgesia
    |September 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Infants tolerated caudal anesthesia with lidocaine or mepivacaine well. This study found that infants can safely receive higher proportional doses of local anesthetics than adults.

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    Area of Science:

    • Pediatric Anesthesiology
    • Pharmacology

    Background:

    • Caudal anesthesia is frequently used in infants for surgical procedures.
    • Determining appropriate local anesthetic dosages for infants is crucial for safety and efficacy.

    Purpose of the Study:

    • To evaluate the safety and efficacy of caudal anesthesia in infants.
    • To compare different local anesthetic agents and dosage calculation methods.

    Main Methods:

    • A randomized study of 70 infants (4-110 weeks old) undergoing routine surgery.
    • Lidocaine 1.5% (n=50) or mepivacaine 1.5% (n=20) was administered via caudal block.
    • Dosage was calculated using an empirical formula (n=35) or body weight (n=35).

    Main Results:

    • Infants tolerated both lidocaine and mepivacaine well.

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  • No significant differences were observed between the dosage calculation methods.
  • Higher proportional doses of local anesthetics were tolerated by infants compared to adults.

    • Conclusions:

    • Caudal anesthesia with lidocaine or mepivacaine is a safe and effective option for infants.
    • Infants demonstrate a higher tolerance for proportional doses of local anesthetics.
    • Dosage calculation based on body weight or empirical formula yielded similar results.