[Serum enzymes and HBsAg in families with viral hepatitis]

Examinations of all families affected with viral hepatitis confirmed by enzyme screening tests by means of incubation and also by the test for HBAgs were carried out in a town district in the course of 7 years. 1. After triple biochemical examinations repeated always after 14 days, changes in the serum enzymes (SGPT, ALD, LDH) were stated in 15% cases from the total of 4328 persons from 1332 families. In the control group no changes were found. 2. From the number of 2215 persons from 726 families 32% were HBAgs-positive in CFT. Simultaneous evidence of HBAgs and enzymes changes were stated in 162 persons (7,4%). 3. Changes in the enzymes as well as simultaneous evidence of HBAgs were especially stated in children. Findings of HBAgs alone prevailed in the adults (P greater than 0,001).