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Second trimester placenta previa. An apparently normal placentation.

P Wexler, K R Gottesfeld

    Obstetrics and Gynecology
    |December 1, 1977
    PubMed
    Summary
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    Many early-pregnancy low-lying placentas or placenta previas resolve by term, indicating they may be normal variants. High parity is linked to placenta previa, but not low-lying placenta, suggesting positional changes during gestation.

    Area of Science:

    • Obstetrics and Gynecology
    • Fetal Medicine
    • Maternal-Fetal Medicine

    Background:

    • Placental positioning is crucial for a healthy pregnancy.
    • Low-lying placenta and placenta previa can pose risks if they persist.
    • Understanding the natural progression of placental position is important for clinical management.

    Purpose of the Study:

    • To investigate the incidence and term outcomes of low-lying placenta or placenta previa identified during genetic amniocentesis.
    • To explore correlations between parity, maternal age, and placental positioning.

    Main Methods:

    • Retrospective review of ultrasound findings in 214 patients undergoing genetic amniocentesis.
    • Analysis of placental positions (low-lying, partial/total placenta previa) in early pregnancy.

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  • Correlation analysis with maternal factors like parity and age, and term outcomes.

    • Main Results:

    • 45% of patients showed a low-lying placenta or placenta previa on early ultrasound.
    • None of these patients required intervention for bleeding or placenta previa at term.
    • High parity (≥4) correlated with increased incidence of partial/total placenta previa, but not low-lying placenta.

    Conclusions:

    • Low-lying placenta and placenta previa identified during early pregnancy may be normal variants.
    • Placental migration is common, and persistence may indicate abnormal implantation.
    • High parity is a risk factor for placenta previa, but not necessarily for a low-lying placenta.