Effect of systemic corticosteroids on antibody-forming cells in the eye and draining lymph nodes

After the intracorneal injection of rabbit eyes with bovine gamma globulin, a systemically administered corticosteroid resulted in the following changes: (1) a reduction in the number of antibody-forming cells in the homolateral uveal tract and cornea; (2) a reduction in the ocular inflammatory response; and (3) a reduction in the number of antibody-forming cells in the draining lymph nodes, if high doses of corticosteroid were given.