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Rheology and anesthesiology.

R J Gordon, M B Ravin

    Anesthesia and Analgesia
    |March 1, 1978
    PubMed
    Summary

    Blood rheology, focusing on viscosity and yield stress, is crucial in anesthesiology. Understanding these factors impacts patient outcomes in critical care, surgery, and thrombosis prevention.

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    Area of Science:

    • Physiology
    • Biomedical Engineering
    • Anesthesiology

    Background:

    • Blood rheology, characterized by non-Newtonian viscosity and yield stress, significantly influences physiological processes.
    • Altered rheological properties can impact vascular resistance, cardiac output, and oxygen transport.

    Purpose of the Study:

    • To review blood rheology principles.
    • To emphasize the application of blood rheology in anesthesiology.
    • To discuss the clinical significance of rheological variables in patient care.

    Main Methods:

    • Literature review of blood rheology.
    • Discussion of rheological variables: viscosity and yield stress.
    • Analysis of clinical implications in anesthesiology.

    Main Results:

    • Blood viscosity directly impacts total peripheral resistance and cardiac output.
    • Elevated hematocrit can decrease oxygen transport due to increased viscosity.
    • Anesthesia can affect blood viscosity by altering venous flow.

    Conclusions:

    • Blood rheology is essential for accurate evaluation of peripheral vascular changes.
    • Understanding blood rheology aids in managing conditions like neonatal respiratory distress and during open-heart surgery.
    • Rheological properties play a role in deep-vein thrombosis pathogenesis.

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