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Related Experiment Videos

Metastatic phycomycosis in a horse.

D R Murray, P W Ladds, R H Johnson

    Journal of the American Veterinary Medical Association
    |April 1, 1978
    PubMed
    Summary

    A Thoroughbred filly developed extensive subcutaneous phycomycosis, a fungal infection, in its hindlimb. The infection, caused by Hyphomyces destruens, was resistant to common treatments and spread to the lymph node.

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    Area of Science:

    • Veterinary Mycology
    • Equine Infectious Diseases

    Background:

    • Phycomycosis is a fungal infection that can affect animals.
    • Subcutaneous phycomycosis in horses can be challenging to treat.

    Observation:

    • A Thoroughbred filly presented with an 8-month history of extensive subcutaneous phycomycosis on the lower hindlimb.
    • The lesion showed no response to treatments including trichlorphon, sodium iodide, and etisazole.
    • Progression of the limb lesion over 3 months was accompanied by an enlarged inguinal lymph node.

    Findings:

    • The enlarged inguinal lymph node exhibited characteristic phycomycotic lesions.
    • A fungus with the morphologic features of Hyphomyces destruens was successfully isolated from both the limb and nodal lesions.
    • This case highlights the diagnostic and therapeutic challenges of equine phycomycosis.

    Implications:

    • Early and accurate diagnosis of Hyphomyces destruens is crucial for effective treatment.
    • Further research into novel therapeutic strategies for subcutaneous phycomycosis in horses is warranted.
    • This case underscores the importance of considering fungal infections in refractory equine limb lesions.

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