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Pericardial angiosarcoma simulating pericardial effusion by echocardiography.

T K Lin, J M Stech, W G Eckert

|June 1, 1978

Summary

A rapidly growing angiosarcoma led to a boy's incapacitation and death within three months. Echocardiograms documented the aggressive tumor's cardiac encasement and metastasis, highlighting a rare cause of echo-free space.

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Area of Science:

Cardiovascular Pathology
Pediatric Oncology
Medical Imaging

Background:

Angiosarcoma is a rare and aggressive malignant vascular tumor.
Pediatric cardiac tumors are uncommon, with angiosarcoma being particularly rare and aggressive.
Echocardiography is a crucial non-invasive tool for diagnosing cardiac and pericardial abnormalities.

Observation:

A fast-growing angiosarcoma caused rapid incapacitation and death in a pediatric patient over three months.
Serial echocardiograms revealed extensive tumor growth encasing the heart within a thick, purplish vascular neoplasm.
The tumor showed extracardiac metastasis, and the heart weighed significantly at 2,000 gm.

Findings:

The case demonstrates the aggressive nature of angiosarcoma in a pediatric patient, leading to rapid deterioration.

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Echocardiographic findings included a thick pericardial neoplasm encasing the heart, distinct from pericardial effusion.

Autopsy confirmed angiosarcoma with significant cardiac involvement and metastasis.

Implications:

This case underscores the importance of considering pericardial tumors in the differential diagnosis of echo-free spaces on echocardiograms.
Early recognition and diagnosis of pediatric cardiac angiosarcoma are critical for potential therapeutic interventions, despite its poor prognosis.
Further research into the pathogenesis and treatment of pediatric angiosarcoma is warranted.