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Hypertrophic cardiomyopathy in the aged

N Krasnow, R A Stein

    American Heart Journal
    |September 1, 1978
    PubMed

    Insights

    Hypertrophic cardiomyopathy frequently affects older adults, with symptoms often misdiagnosed. This suggests a potentially more favorable disease course for some patients, impacting clinical management strategies.

    Area of Science:

    • Cardiology
    • Geriatric Medicine

    Background:

    • Hypertrophic cardiomyopathy (HCM) is typically associated with younger individuals.
    • However, HCM can also present in older populations, often with atypical presentations.

    Purpose of the Study:

    • To investigate the prevalence and characteristics of hypertrophic cardiomyopathy in an elderly patient cohort.
    • To compare clinical presentations and diagnostic findings of HCM in older versus younger patients.

    Main Methods:

    • Retrospective analysis of 23 hypertrophic cardiomyopathy cases over 2.5 years.
    • Inclusion of patients aged 65 years and older.
    • Cardiac catheterization and echocardiography for obstructive component assessment.

    Main Results:

    • 20 of 23 HCM cases were in patients aged 65-76 years.
    • 16 of these older patients had obstructive HCM.
    • Symptoms were often misattributed to other conditions like aortic stenosis or hypertensive heart disease.

    Conclusions:

    • Hypertrophic cardiomyopathy is not uncommon in older adults, predominantly females.
    • The disease may present with few or no symptoms until late in life.
    • Clinical management should consider this potentially indolent course in older patients.

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