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The study reveals a significant increase in the male-to-female sex ratio among infant deaths during the perinatal period, particularly after birth. This highlights a shift in sex-linked mortality patterns from the antenatal to the postnatal stage.
Area of Science:
- Reproductive Biology
- Perinatal Medicine
- Human Demography
Context:
- The perinatal period is a critical phase for infant survival.
- Understanding sex-specific mortality patterns is crucial for public health.
- Previous research indicates higher male mortality in later life stages.
Purpose:
- To investigate sex ratio variations across different perinatal phases (antenatal, intranatal, postnatal).
- To identify statistically significant differences in sex-specific mortality during the perinatal period.
- To analyze the manifestation of differential sex-linked mortality from extrauterine life onwards.
Summary:
- Analysis of 11,500 infant deaths across antenatal, intranatal, and postnatal periods.
- Observed sex ratios: 107 M:100 F (antenatal), 136 M:100 F (intranatal), 168 M:100 F (postnatal).
- Statistically significant increases in male mortality were noted at each stage (p < 0.001), especially post-birth.
Impact:
- Demonstrates a distinct shift in sex-linked mortality during the perinatal phase.
- Suggests that higher male mortality, typical of postnatal development, begins immediately after birth.
- Provides critical data for targeted interventions in perinatal care and infant health.
Abstract:
Sex ratio in 11,500 infants died at different perinatal periods (antenatal, intranatal and postnatal) is studied. Sex ratio in these periods is: 107 male : 100 female; 136 male : 100 female; 168 male : 100 female respectively; differences at each period are statistically significant (alpha less than 0.001). A change in differential sex-linked mortality is observed at perinatal period. High mortality in males, which is characteristic of human postnatal ontogenesis, manifests distinctly from the moment of passing on to extrauterine life.