Absence of the d triradius

Area of Science:

• Dermatoglyphics
• Human genetics
• Medical diagnostics

Background:

• Dermatoglyphics, the study of skin patterns, offers insights into human development and potential genetic anomalies.
• The d triradius is a key feature in palm print analysis, and its absence can be associated with certain genetic conditions.

Purpose of the Study:

• To report cases of absent d triradius.
• To investigate the association of absent d triradius with congenital heart disease and the 49, XXXXY constitution.

Main Methods:

• Analysis of dermatoglyphs from 3610 subjects.
• Comparison of absent d triradius incidence in normal controls, subjects with congenital heart disease, and individuals with 49, XXXXY karyotype.

Main Results:

• Ten cases of absent d triradius were identified in the study cohort.
• A higher prevalence was noted in subjects with congenital heart disease (3/800) and those with 49, XXXXY (2/2).
• One case was observed in 1000 normal controls, and discordant monozygous twins were identified.

Conclusions:

• The absence of the d triradius may serve as a potential indicator for genetic abnormalities.
• Further research is warranted to explore the diagnostic significance of absent d triradius in clinical settings.