Serum LDH-5 in carriers of Duchenne muscular dystrophy

We failed to confirm the suggestion that serum lactate dehydrogenase isoenzyme 5 (LDH-5) levels are as sensitive an indicator of the carrier status in Duchenne muscular dystrophy (DMD) as are serum levels of creatine kinase. In particular, serum LDH-5 was not increased in carriers when the serum creatine kinase level was normal.