Effects of methomyl and ethanol on behavior in the Sprague-Dawley rat

Emotional behavior and activity levels were studied following administration of ethanol and/or a carbamate pesticide, methomyl, to rats via a ground chow diet. Acetylcholinesterase levels were lowered following the experimental diets. The group having the greatest reduction in AChE, the methomyl group, showed less evidence for habituation in an open-field test. No differences relative to control subjects were noted on handling and muricide tests.