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Persistent neurologic sequelae of migraine: a case report
Neurology
|August 1, 1979
Summary
A young man experienced multiple cerebral infarctions linked to hemiplegic migraine. This rare condition, potentially exacerbated by propranolol dosage changes, highlights migraine as a possible cause of stroke.
Area of Science:
- Neurology
- Vascular Neurology
- Neuroscience
Background:
- Cerebral infarctions are typically associated with vascular risk factors.
- Migraine, particularly hemiplegic migraine, is an uncommon cause of ischemic stroke.
- Basilar artery involvement suggests potential for severe neurological events.
Observation:
- A 32-year-old male presented with multiple cerebral infarctions.
- The patient had a history of basilar artery migraine and hemiplegic migraine.
- One infarction event coincided with a reduction in propranolol dosage.
Findings:
- Computerized tomography confirmed both old and new infarcts in the brain.
- Standard laboratory tests including platelet aggregation and coagulation studies were unremarkable.
- No other identifiable cause for the cerebral infarcts was found.
Implications:
- This case suggests a potential causal link between hemiplegic migraine and cerebral infarction.
- The role of migraine in stroke etiology warrants further investigation.
- Clinical management of migraine patients, especially those with basilar or hemiplegic subtypes, should consider stroke risk.