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Interaction of DNA with a porphyrin ligand: evidence for intercalation
Nucleic Acids Research
|July 11, 1979
Abstract:
The porphyrin photosensitizer, meso-Tetra (4-N-methylpyridyl) porphine tetraperchlorate binds to calf thymus DNA by intercalation and by external electrostatic association. This was concluded from the results of measruements involving Scatchard analysis, viscometry, thermal denaturation, and circular dichroism.