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Employment of bis-intercalating dyes for the "in situ" study of DNA composition
Basic and Applied Histochemistry
|January 1, 1979
Abstract:
Spectrofluorometric characteristics of DNA-RO4 complexes have been studied in order to evaluate the possibility of employment of RO4 (a bis-intercalating dye) for the determination of the DNA base composition. The results have shown the usefulness of this compound for DNA with AT percentage between 30% and 60%. RO4 has been also applied to the study of the chromosome banding mechanism.