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Activation of Hageman factor by L-homocystine

Science (New York, N.Y.)
|November 29, 1968
PubMed

L-Homocystine activates Hageman factor, as demonstrated by its capacity to initiate clotting and to induce the evolution of plasma kinins. Perhaps, strategically located deposits of this amino acid are responsible for the unusual frequency of thrombosis in patients with homocystinuria.

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