Lipoprotein lipase activity in the skeletal muscle during physical exercise in dogs

Changes in lipoprotein lipase activity /LPLA/ in the quadriceps femoris muscle were followed in ten dogs during 3-hour treadmill exercise and 2-hour post-exercise recovery period. During the first hour of exercise muscle LPLA steeply increased. Subsequently the enzyme activity tended to plateau. After exercise LPLA decreased to the pre-exercise value within 1 hour. It is concluded that exercise increases the ability of skeletal muscles to remove triglycerides from the circulation.