[Female hyperprolactinaemia. 19 cases (author's transl)].

Area of Science:

• Endocrinology
• Reproductive Medicine

Background:

• Hyperprolactinemia, a condition of elevated prolactin levels, can disrupt ovarian function and fertility.
• Previous treatments, including vitamin B6, have shown limited efficacy.

Purpose of the Study:

• To evaluate the effectiveness of vitamin B6 and bromocriptine in managing hyperprolactinemia and restoring ovarian function.
• To assess the role of surgical intervention in cases resistant to medical treatment.

Main Methods:

• Observational study analyzing patient outcomes.
• Comparison of treatment responses to vitamin B6, bromocriptine, and surgical interventions.

Main Results:

• Vitamin B6 did not demonstrate effectiveness in correcting hyperprolactinemia.
• Bromocriptine administration led to immediate or subsequent restoration of ovarian function.
• Surgical treatment failure was overcome by bromocriptine therapy.

Conclusions:

• Vitamin B6 is not an effective treatment for hyperprolactinemia.
• Bromocriptine is a highly effective agent for normalizing prolactin levels and restoring reproductive function.
• The precise role of surgery in managing hyperprolactinemia requires further investigation.