Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Decrease in serum levels of retinol and its binding protein (RBP) in infection].

G Arroyave, M Calcaño

    Archivos Latinoamericanos De Nutricion
    |June 1, 1979
    PubMed
    Summary

    Infections significantly lower blood serum levels of retinol and retinol-binding protein (RBP), particularly in children. This highlights a critical public health concern for vitamin A deficiency in vulnerable populations.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Protein and fat balance studies in children recovering from kwashiorkor.

    Journal of tropical pediatrics (London, England : 1955)·2014
    Same author

    Agricultural and food policies. Some concerns regarding their nutritional relevance.

    Archivos latinoamericanos de nutricion·1995
    Same author

    [Food fortification with emphasis on the addition of micronutrients to wheat flour].

    Archivos latinoamericanos de nutricion·1993
    Same author

    American Journal of Clinical Nutrition, Volume 9, 1961: All-vegetable protein mixtures for human feeding.

    Nutrition reviews·1989
    Same author

    [3 problem vitamins in Latin America].

    Archivos latinoamericanos de nutricion·1988
    Same author

    [Abuse of megadoses of vitamins].

    Archivos latinoamericanos de nutricion·1988

    Area of Science:

    • Nutrition and Metabolism
    • Infectious Diseases
    • Clinical Biochemistry

    Background:

    • Low serum retinol levels are prevalent in underdeveloped regions, especially among children.
    • Infectious episodes can exacerbate nutritional deficiencies, posing significant health risks.

    Purpose of the Study:

    • To investigate the impact of various infections on serum retinol and retinol-binding protein (RBP) levels.
    • To assess changes in other blood serum components, including carotene, proteins, albumin, and globulins, during infection.

    Main Methods:

    • Studied 24 children and 30 adults experiencing infections like chickenpox, bronchitis, and upper respiratory infections.
    • Measured serum levels of retinol, RBP, carotene, total proteins, albumin, and globulins before and during infection.

    Main Results:

    • Infections markedly reduced serum retinol levels, often by over 20-30 micrograms/dl.
    • Serum RBP levels showed a significant positive correlation with retinol, decreasing proportionally with infection.
    • Serum albumin decreased during infections, while children's globulin levels increased; carotene levels remained stable.

    Conclusions:

    • Infectious episodes significantly deplete serum retinol and RBP, increasing the risk of clinical vitamin A deficiency, especially in children with pre-existing low levels.
    • Fever intensifies the negative effects of infections on these crucial nutrient levels.
    • Findings underscore the public health importance of managing infections to prevent severe vitamin A deficiency in at-risk populations.

    Related Experiment Videos