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Fine structure of post-mortal tissues transformations. Preliminary observations
Bollettino Della Societa Italiana Di Biologia Sperimentale
|September 30, 1979
Summary
Corification, a post-mortal skin change, preserves some cell structures but damages others. This suggests enzymatic activity is significantly inhibited during this transformation.
Area of Science:
- Histology
- Cell Biology
- Forensic Science
Background:
- Post-mortal changes in human tissues are complex.
- Understanding cellular preservation is crucial in forensic and medical studies.
Purpose of the Study:
- To investigate the ultrastructural changes in human skin during corification.
- To determine the state of cellular components after this anomalous post-mortal transformation.
Main Methods:
- Transmission electron microscopy was used to examine human skin samples.
- Detailed ultrastructural analysis focused on various cellular components.
Main Results:
- Cell membranes, desmosomes, mitochondria, and nuclear envelopes showed good preservation.
- The endoplasmic reticulum exhibited significant disruption and alteration.
- Other cellular structures displayed varying degrees of degradation.
Conclusions:
- Corification involves selective preservation and degradation of cellular ultrastructure.
- The findings suggest a marked inhibition of both endogenous and exogenous enzymatic actions during corification.