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Related Experiment Videos

Cerebrospinal fluid imaging using serial metrizamide CT cisternography.

B P Drayer, A E Rosenbaum, H B Higman

    Neuroradiology
    |March 28, 1977
    PubMed
    Summary
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    Serial CT cisternography with metrizamide (Amipaque) helps analyze cerebrospinal fluid (CSF) flow in dementia patients. Abnormal patterns, including ventricular reflux and stasis, indicate communicating hydrocephalus.

    Area of Science:

    • Neurology
    • Radiology
    • Neurosurgery

    Background:

    • Dementia evaluation often includes CT scanning.
    • Communicating hydrocephalus can present with dementia symptoms.
    • Cerebrospinal fluid (CSF) kinetics are crucial for diagnosing hydrocephalus.

    Purpose of the Study:

    • To analyze CSF kinetics using serial metrizamide CT cisternography.
    • To identify characteristic patterns of abnormal CSF flow in patients.

    Main Methods:

    • Twenty-five patients with dementia underwent serial CT cisternography.
    • Metrizamide (Amipaque) was used as a contrast agent.
    • CSF flow patterns were assessed over time.

    Main Results:

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  • Delayed CSF flow patterns were observed in 7 patients.
  • Intermediate patterns were noted in 4 patients.
  • Abnormal cisternograms showed ventricular reflux, stasis, diminished parasagittal blush, and periventricular decreased absorption.

    • Conclusions:

    • Serial metrizamide CT cisternography is effective for monitoring CSF kinetics.
    • Distinct patterns can suggest communicating hydrocephalus in dementia patients.
    • This technique aids in dynamic assessment when hydrocephalus is suspected.