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Milk and lactose-hydrolyzed milk.

D Payne-Bose, J D Welsh, H L Gearhart

The American Journal of Clinical Nutrition

|May 1, 1977

Summary

This summary is machine-generated.

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Hydrolyzing lactose in nonfat dry milk significantly reduced breath hydrogen response in lactose malabsorbers. This indicates pre-digested lactose improves tolerance, aiding individuals with lactose malabsorption.

Area of Science:

Gastroenterology
Human Nutrition
Biochemistry

Background:

Lactose malabsorption affects a significant portion of the global population.
Lactose intolerance symptoms arise from undigested lactose reaching the colon.
Breath hydrogen testing is a standard method to assess lactose digestion.

Purpose of the Study:

To evaluate the impact of pre-hydrolyzed lactose on breath hydrogen response in lactose malabsorbers.
To compare the digestive tolerance of standard nonfat dry milk versus lactose-hydrolyzed nonfat dry milk.

Main Methods:

Seven lactose malabsorbent females (mean age 23) participated in a crossover study.
Test meals included standard nonfat dry milk and nonfat dry milk with 92% lactose hydrolysis.
Lactose malabsorption was assessed using the breath hydrogen test over 3-hr and 5-hr periods, with duplicate testing.

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Main Results:

The average breath hydrogen response was significantly lower (P < 0.002) after consuming lactose-hydrolyzed milk compared to standard milk.
Individual responses showed significant variability (P < 0.06-0.09) but no significant differences between duplicate test days.

Conclusions:

Pre-hydrolyzing lactose in nonfat dry milk substantially reduces gas production in lactose malabsorbers.
This suggests that consuming lactose-hydrolyzed dairy products can improve digestive tolerance for individuals with lactose malabsorption.