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Disciform detachment of the macula. I. Juvenile haemorrhagic macular choroidopathy
Insights
Juvenile haemorrhagic macular choroidopathy may stem from intravascular coagulation. Early treatment with acetylsalicylic acid and lasercoagulation shows promise for this condition with poor visual outcomes.
Area of Science:
- Ophthalmology
- Vascular Biology
Background:
- Juvenile haemorrhagic macular choroidopathy is a rare condition affecting young individuals.
- The etiology of this condition is not fully understood, but potential links to vascular events are being investigated.
Purpose of the Study:
- To describe the clinical findings in patients with juvenile haemorrhagic macular choroidopathy.
- To investigate potential causes and evaluate treatment outcomes for this condition.
Main Methods:
- Clinical case series describing six patients.
- Review of patient history, clinical features, and disease course.
- Evaluation of treatment responses to oral corticosteroids, acetylsalicylic acid, and lasercoagulation.
Main Results:
- No evidence of Histoplasma capsulatum infection was found.
- Intravascular coagulation in the central choriocapillaris is suggested as a potential cause.
- Oral corticosteroids did not prevent disease progression, leading to poor visual outcomes.
- One patient showed a positive response to acetylsalicylic acid.
Conclusions:
- Juvenile haemorrhagic macular choroidopathy may be associated with intravascular coagulation.
- Acetylsalicylic acid, potentially combined with lasercoagulation, may offer therapeutic benefits in early stages.
Abstract:
The clinical findings in six patients with juvenile haemorrhagic macular choroidopathy are described. There was no evidence of infection with Histoplasma capsulatum. The history, clinical features and course of the disease suggested that at least in some cases intravascular coagulation in the central choriocapillaris may form the choroidopathy inducing the disciform detachment of the macula. Oral corticosteroids could not prevent progression of the lesion which had a poor visual outcome. In one patient, good therapeutic response was achieved with acetylsalicylic acid, which may be useful together with lasercoagulation in the early treatment of this syndrome.