Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Corneal ulcer caused by Pasteurella multocida.

J J Purcell, J H Krachmer

    American Journal of Ophthalmology
    |April 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    A dog-related eye injury led to a severe corneal ulcer in a Graves' disease patient. Pasteurella multocida, transferred from the patient, caused a similar ulcer in a rabbit model, highlighting zoonotic potential.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Toxic corneal oedema associated with amantadine use.

    The British journal of ophthalmology·2009
    Same author

    The effects of donor age on the outcome of penetrating keratoplasty in adults.

    Ophthalmology·1997
    Same author

    The role of topical corticosteroids in the management of Acanthamoeba keratitis.

    Cornea·1997
    Same author

    Confocal microscopy findings of Acanthamoeba keratitis.

    American journal of ophthalmology·1996
    Same author

    Mottled cyan opacification of the posterior cornea in contact lens wearers.

    American journal of ophthalmology·1995
    Same author

    Bilateral herpes simplex virus type 2 keratitis: a clinicopathologic report with immunohistochemical and ultrastructural observations.

    German journal of ophthalmology·1995

    Area of Science:

    • Ophthalmology
    • Microbiology
    • Zoonotic Diseases

    Background:

    • Graves' disease and exophthalmos can increase ocular surface vulnerability.
    • Ocular trauma, even minor, can predispose to microbial keratitis.

    Observation:

    • A 44-year-old woman with Graves' disease and exophthalmos sustained a corneal ulcer after ocular trauma from a pet dog.
    • Pasteurella multocida was identified as the causative agent of the corneal ulcer.

    Findings:

    • Experimental transfer of Pasteurella multocida from the patient to an abraded rabbit cornea successfully replicated a similar corneal ulcer and hypopyon.
    • This demonstrates the pathogenicity of Pasteurella multocida in corneal infections.

    Implications:

    Related Experiment Videos

  • Highlights the risk of zoonotic transmission of ocular pathogens from pets to humans.
  • Emphasizes the importance of considering animal contact in cases of severe microbial keratitis, especially in immunocompromised or predisposed individuals.
  • Suggests Pasteurella multocida as a potential cause of severe keratitis following minor ocular trauma.