Studies on the lissamine green distribution in three model rat tumors

In order to gain knowledge on the extent of distribution of chemotherapeutical agents through the blood systems of various tumors, we studied as an indicator the lissamine green concentrations in various tumor segments after different exposure times. As model tumors we used the autochthonic benzpyrene fibrosarcoma and the transplantable tumors Walker and Yoshida in Sprague-Dawley rats. Remarkable differences in the providing blood vessel were observed.