Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Early venous thrombosis: A scanning electron microscopic study.

T K Day, S V Cowper, V V Kakkar

    Thrombosis and Haemostasis
    |June 30, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Getting the best of both worlds--clinical excellence at a peripheral unit.

    Journal of the Royal Army Medical Corps·2008
    Same author

    An observational study on the spectrum of heat-related illness, with a proposal on classification.

    Journal of the Royal Army Medical Corps·2005
    Same author

    Differing opinions on treatment of immune-mediated hemolytic anemia.

    Journal of the American Veterinary Medical Association·2001
    Same author

    A patient education MAP: an integrated, collaborative approach for rehabilitation.

    Rehabilitation nursing : the official journal of the Association of Rehabilitation Nurses·1999
    Same author

    Haemostatic factors and risk of coronary heart disease.

    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis·1999
    Same author

    Chronic fatigue syndrome: physical and cardiovascular deconditioning.

    QJM : monthly journal of the Association of Physicians·1998

    Minimal electric charge initiates thrombosis in rabbit veins within minutes. Fibrin meshwork formation and platelet clumps appear on unaltered endothelium, observed via scanning electron microscopy.

    Area of Science:

    • Vascular Biology
    • Biomedical Engineering
    • Microscopy

    Background:

    • Thrombosis is a critical factor in cardiovascular diseases.
    • Understanding early thrombotic events is crucial for developing preventative strategies.
    • Minimal electric charge as an initiator of thrombosis is not well-characterized.

    Purpose of the Study:

    • To investigate the initial events of thrombosis induced by minimal electric charge in rabbit femoral veins.
    • To visualize the real-time formation of thrombus using scanning electron microscopy.

    Main Methods:

    • Induction of thrombosis using a minimal electric charge in rabbit femoral veins.
    • Observation of thrombus formation using scanning electron microscopy (SEM).

    Related Experiment Videos

    Main Results:

    • Thrombosis initiated within ten minutes after electric charge application.
    • Initial thrombus formation occurred on an apparently unaltered endothelium.
    • The sequence of events included fibrin meshwork deposition followed by platelet clump aggregation.

    Conclusions:

    • Minimal electric charge can rapidly trigger thrombosis in vivo.
    • The early stages of thrombosis involve fibrin deposition and platelet aggregation.
    • SEM provides valuable insights into the dynamic process of thrombus formation.