Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Changing values for the normal thyroid radioactive iodine uptake test.

E T Wong, A L Schultz

    JAMA
    |October 17, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Study protocol for OptimalTTF-2: enhancing Tumor Treating Fields with skull remodeling surgery for first recurrence glioblastoma: a phase 2, multi-center, randomized, prospective, interventional trial.

    BMC cancer·2021
    Same author

    Dexamethasone exerts profound immunologic interference on treatment efficacy for recurrent glioblastoma.

    British journal of cancer·2015
    Same author

    Diagnostic Accuracy of PET, SPECT, and Arterial Spin-Labeling in Differentiating Tumor Recurrence from Necrosis in Cerebral Metastasis after Stereotactic Radiosurgery.

    AJNR. American journal of neuroradiology·2015
    Same author

    Dexamethasone exerts profound immunologic interference on treatment efficacy for recurrent glioblastoma.

    British journal of cancer·2015
    Same author

    Nuclear factor κB (NF-κB) suppresses food intake and energy expenditure in mice by directly activating the Pomc promoter.

    Diabetologia·2013
    Same author

    Personalized medicine for glioblastoma: current challenges and future opportunities.

    Current molecular medicine·2013
    Same journal

    WHO Issues Guidelines for Treating Ebola and Marburg Viruses.

    JAMA·2026
    Same journal

    FDA Approves Additional Naloxone Nasal Spray for Opioid Overdose.

    JAMA·2026
    Same journal

    HIV May Hide in More Cells Than Previously Thought-Here's What That Could Mean for a Cure.

    JAMA·2026
    Same journal

    US Dietary Supplement Use Increasing, Especially in Older Adults.

    JAMA·2026
    Same journal

    Heat Stress From Climate Change Surges Globally.

    JAMA·2026
    Same journal

    Strength Training Linked With Lower Cardiovascular Disease Risk in Women.

    JAMA·2026
    See all related articles

    Thyroid radioactive iodine uptake has shifted significantly in Minneapolis over 20 years. A decrease in dietary iodine, particularly from bread, is the likely cause of these changes in thyroid function.

    Area of Science:

    • Endocrinology
    • Nuclear Medicine
    • Nutritional Science

    Background:

    • Thyroid radioactive iodine (RAI) uptake values indicate thyroid gland function.
    • Normal ranges for RAI uptake have shown significant shifts over time in the Minneapolis area.
    • Previous studies documented RAI uptake values in 1957 and 1971.

    Purpose of the Study:

    • To investigate the recent changes in normal thyroid radioactive iodine uptake values.
    • To identify potential factors contributing to the observed shifts in RAI uptake.
    • To analyze the iodine content of locally available bread products.

    Main Methods:

    • Collected 24-hour thyroid RAI uptake data from normal subjects in the Minneapolis area.
    • Compared current RAI uptake data with historical data from 1957 and 1971.

    Related Experiment Videos

  • Quantified the iodine content of commercially baked white bread available in the area.

    • Main Results:

    • The mean 24-hour thyroid RAI uptake was 20.5% +/- 6.1% in 1975, a decrease from 11.5% +/- 4.4% in 1971.
    • Historical data showed a mean uptake of 25% +/- 8% in 1957.
    • The average iodine content in a slice of white bread was found to be 26 micrograms.

    Conclusions:

    • The observed shift in thyroid RAI uptake values between 1971 and 1975 is likely linked to a reduction in dietary iodine intake.
    • Decreased iodine content in commercially available white bread may be a significant factor.
    • Dietary iodine levels can influence thyroid function and require ongoing monitoring.