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[Acidosis and clinical condition in asphyctic calves]
Berliner Und Munchener Tierarztliche Wochenschrift
|October 1, 1977
Summary
Depressed calves exhibit combined respiratory-metabolic acidosis at birth. Metabolic adaptation occurs within 6 hours, while respiratory acidosis persists for 24 hours, impacting calf health.
Area of Science:
- Veterinary Medicine
- Neonatal Physiology
- Animal Science
Context:
- Neonatal calf depression is a critical concern in livestock production.
- Understanding acid-base balance in newborn calves is crucial for assessing health and survival.
- The modified APGAR score is used to evaluate neonatal well-being.
Purpose:
- To investigate the acid-base status of depressed newborn calves.
- To characterize the temporal changes in respiratory and metabolic acidosis.
- To correlate acid-base parameters with clinical condition (APGAR score).
Summary:
- Depressed calves (APGAR score 4-6) present with combined respiratory-metabolic acidosis at birth (pH 7.082, pCO2 73.3 mmHg, BE -10.6 mmol/l).
- Metabolic acidosis resolves within 6 hours, but respiratory acidosis persists up to 24 hours post-delivery.
- Significant deviations in pH, base excess, and bicarbonate levels are observed compared to normal calves throughout the study period.
Impact:
- Provides critical insights into the pathophysiology of neonatal calf depression.
- Highlights the prolonged respiratory component of acidosis in affected calves.
- Establishes a correlation between the 1-minute APGAR score and key acid-base parameters, aiding in early diagnosis and intervention.