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Supplemented fasting as a large-scale outpatient program.

V Vertes, S M Genuth, I M Hazelton

    JAMA
    |November 14, 1977
    PubMed
    Summary
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    Supplemented fasting effectively reduces weight in massively obese individuals. This outpatient regimen led to significant weight loss (78% lost over 18.2 kg) with good tolerance and few side effects.

    Area of Science:

    • Obesity Management
    • Nutritional Science
    • Metabolic Health

    Background:

    • Supplemented fasting is recognized for substantial weight reduction in obesity.
    • Adapting this treatment to outpatient settings is crucial for broader application.
    • Massively obese individuals often require effective, large-scale treatment options.

    Purpose of the Study:

    • To evaluate the efficacy and tolerability of a large-scale supplemented fasting regimen for massively obese outpatients.
    • To determine the rate and extent of weight loss in this patient population.
    • To assess the feasibility of daily activities and side effect profile during outpatient treatment.

    Main Methods:

    • A cohort of 519 massively obese patients were treated using a supplemented fasting regimen in an outpatient setting.

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  • Weight loss, rate of weight loss (kg/wk), and patient-reported side effects were monitored.
  • Patient adherence and ability to maintain daily activities were assessed.

    • Main Results:

    • 78% of patients achieved a minimum weight loss of 18.2 kg.
    • The overall average weight loss rate was 1.5 kg/wk (females: 1.3 kg/wk, males: 2.1 kg/wk).
    • Most patients tolerated the regimen well, continuing daily activities with no serious adverse events.

    Conclusions:

    • Supplemented fasting is an effective and well-tolerated outpatient treatment for substantial weight reduction in massively obese individuals.
    • The regimen demonstrates feasibility for large-scale application, supporting its wider use in clinical practice.
    • Outpatient supplemented fasting offers a viable strategy for managing severe obesity with significant weight loss outcomes.